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Estro-Mend™ |
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A synergistic
combination of isoflavones, phytoestrogens & other herbs to naturally support optimal estrogen function. |
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· Favorably affects estrogen receptors, supporting healthy estrogen
function.♦ |
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· Promotes healthy estrogen metabolism including 2-hydroxylation which may protect estrogen sensitive tissues.♦ |
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· Promotes healthy function of bone, heart, brain, breasts, vagina and
other estrogen sensitive tissues.♦ |
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· Relieves many of the physical and psychological symptoms of menopause,
such as hot flushes/night sweats, irritability, sleep disturbances, vaginal
symptoms, mood swings & memory problems.♦ |
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· May use without estrogen, or with bioidentical estrogen to support
healthy estrogen function.♦ |
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Three Capsules Contain: |
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Isoflavone Complex Proprietary
Blend |
375
mg |
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Pueraria lobata
root, Red
Clover flowering tops standardized to 8% isoflavones & soy isoflavone
concentrate NovaSoy® min. 40% isoflavones |
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Black Cohosh (standardized) |
60mg |
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standardized
to 8% triterpene glycosides |
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Estro-Mend™ Herbal Proprietary Blend |
1,185 mg |
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Bacopa Monniera (standardized to 20% bacopasides, leaf), Cranberry fruit, Dong
Quai (root), Schisandra (standardized to 0.9% schisandrins,
fruit & seeds), Sage (Salvia officinalis, leaf) and Hops (aerial
parts) |
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Suggested
Use: |
3
daily with food |
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Also See: |
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MORE INFORMATION on the
Constituents of Estro-Mend™ |
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Isoflavone Complex: Isoflavones are a class of
phytoestrogens — plant-derived compounds that are similar in structure and/or
function to human estrogens. In plants, isoflavones are usually bound to
glycosides. During digestion, colonic bacteria are thought to metabolize the
inactive isoflavone glycosides into their active counterparts. Genistein and daidzein, two of the predominant isoflavones that are
beneficial to health, are present in significant concentrations in soy, Pueraria lobata (Kudzu) and red
clover. These isoflavones promote the 2-hydroxylation pathway, increasing
“good estrogens”. Red Clover provides additional isoflavones (such as
biochanin A, & formononetin), while Pueraria provides additional isoflavones (such as daidzin,
puerarin & 3'-methoxypuerarin) which also contribute to this isoflavone
complex. Isoflavones have both weak estrogenic and antiestrogenic activity,
which may contribute to their ability to diminish menopausal symptoms and
support maintenance of bone mineral density. Isoflavones may also help protect
the cardiovascular system, support the immune system, inhibit angiogenesis,
and protect against oxidative damage as antioxidants.♦ |
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Black Cohosh: The active constituents of Black
Cohosh include the isoflavone formononetin, as well as triterpenoids,
cimicifugoside, and cinnamic
acid derivatives (ferulic acid, isoferulic
acid, and piscidic and fukiic
esters). Black Cohosh appears to regulate estrogen levels, thereby
normalizing hormonal balance and moderating the symptoms that accompany fluctuating
hormone levels. Black cohosh extracts have exhibited organ specific
estrogenic effects and have been characterized as selective estrogen-receptor
modulators. Black Cohosh may suppress excessive secretion of luteinizing
hormone (LH). Sudden increases in LH secretion, which occur in response to
declining estrogen levels, appear largely responsible for many symptoms
associated with menopause, such as hot flashes, night sweats, insomnia,
irritability, heart palpitations, and headaches. As with other estrogenic
compounds, the active constituents in Black Cohosh extract may have
beneficial effects in the cardiovascular and skeletal systems of
postmenopausal women. As such, Black Cohosh offers a safe and natural method
of balancing fluctuating hormone levels and easing the resulting symptoms
that can occur during menopause.♦ |
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Bacopa monniera:
Bacopa
monniera possesses a potent adaptogenic activity
helping the body adapt to both acute and chronic stress. It has been used for
memory enhancement, insomnia and as a mild sedative. It is also recognized as
a potent antioxidant. This antioxidant capacity of Bacopa may explain, at
least in part, the reported antistress, immunomodulatory,
cognition-facilitating, anti-inflammatory and antiaging effects. Human
studies have shown that the actions of Bacopa on cognitive functioning in
normal healthy subjects, including significant improvement in speed of visual
information processing, learning rate and memory consolidation, have maximal
effects evident after 12 weeks. Both acquisition and retention of memory
showed improvement with a significant effect on the retention of new
information and a decreased rate of forgetting of newly acquired information.
Animal studies also
suggest it may have a thyroid-stimulating role.♦ |
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Cranberry fruit: Cranberry juice has long been
recognized for its role in supporting urinary tract health. However, when the
whole fruit is used the benefits may extend much further than urinary tract
health. The fruit also contains proanthocyanins and anthocyanins, two
bioflavonoids known for their antioxidant activity. Anthocyanins repair and
protect DNA integrity and may be beneficial in reducing age-associated
oxidative stress, as well as in improving neuronal and cognitive brain
function. Polyphenolic compounds in cranberries have been investigated to
determine their role in protection against cardiovascular disease and some
cancers. Antioxidant & Antiproliferation activities have also been
attributed to cranberry fruit.♦ |
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Dong Quai root: Don Quai, long regarded as a
“female tonic” or “female adaptogen”, has profound benefit in women’s health.
Through its phytoestrogenic action it can decrease symptoms in menopause. It
can increase vaginal lubrication and may increase sexual activity. It may
also increase mucus protection of the digestive system. Normal intestinal
mucus is required for proper bowel function and for immune system health. The
immunostimulatory, anti-inflammatory and antiallergenic properties of Don
Quai may support immune system health. Don Quai may promote reformation of
bone and has demonstrated anti-atherosclerotic action. While able to
contribute to health and proper function of so many tissues, it has shown
very weak estrogen receptor binding and does not produce estrogen-like
responses in endometrial thickness.♦ |
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Hops: (Humulus lupulus) Hops has been used to reduce hot flashes
in menopausal women and is considered effective in mood disturbances such as
restlessness and anxiety, and sleep disturbances. Some of the compounds that
occur in hops have very strong phytoestrogenic activity such as 8-prenylnaringenin, which may have a
preventive effect against breast and ovarian cancer. The hop bitter acids may
be responsible for the chemopreventive action of hops. A catechin trimer in
Humulus lupulus actually exhibits antioxidant
activity greater than alpha-tocopherol or ascorbic acid. Despite the
anti-cancer properties that have been attributed to hops, its constituents
may weakly bind to estrogen receptors alpha (ER alpha) and beta (ER beta) and
exhibit mild estrogenic activity and up-regulation of progesterone receptors
(PR), which may explain why it effectively relieves menopause symptoms.♦ |
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Sage: Sage (Salvia
officinalis) contains phytoestrogen substances that make it very
useful for women. It has been used to treat hot flashes and to decrease
perspiration in both daytime and night-time excessive sweating. Sage has a
positive effect on the nervous system. Human studies have shown it may be
even be beneficial in the management of mild to moderate Alzheimer's disease
and can provide memory-improving properties. Sage binds to the
GABA/benzodiazepine receptor complex in brain tissue and has demonstrated
calming actions, even in agitated patients. Antioxidant glycosides from sage shown free
radical scavenging activity, which may contribute to its benefits.♦ |
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Schisandra:
Schisandra may be
described as an adaptogen that supports the normal function of the nervous
system, while supporting cardiovascular health. It also has anti-oxidant and
hepatoprotective properties. Lignans in Schisandra such as schisanhenol may
be responsible for its actions. Used for the treatment of cardiovascular
diseases, liver diseases, diseases of the CNS related to the old age,
Schisandra demonstrated a beneficial effect on memory registration and memory
consolidation, and may be useful to prevent age associated degeneration of
the brain.♦ |
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♦ These statements have not been evaluated by the
Food and Drug Administration. |
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Estro-Mend™ is a
Trademark of Douglas Laboratories. All Rights Reserved. |
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